A database of hormones and their receptors
Peptide Hormone

Search Result - 1

HMRbase accession number10113
Swiss-prot Accession numberQ6BEG6 (Sequence in FASTA format)
DescriptionAppetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Contains: Ghrelin; Obestatin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the motilin family.
Tissue SpecificityN/A
Post translational modification O-n-octanoylation is essential for ghrelin activity (By similarity). Amidation of Leu-98 is essential for obestatin activity (By similarity).
FunctionGhrelin is the ligand for growth hormone secretagogue receptor type 1 (GHSR). Induces the release of growth hormone from the pituitary. Has an appetite-stimulating effect, induces adiposity and stimulates gastric acid secretion. Involved in growth regulation
Protein Length117 Amino acids
Molecular weight12956
References1   Lin X., Miyazato M., Kaiya H., Ida T., Kangawa K.; "cDNA cloning of feline and caprine ghrelin."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Domain NameMotilin_assoc  Motilin_ghrelin  
Hormone NameGhrelin
Mature Hormone SequenceGSSFLSPEHQKVQQRKESKKPPAKLQPR
Position of mature hormone in Pre-Hormone protein28 Residues from position (24-51)
ReceptorN/A
Gene ID493844      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 2

HMRbase accession number10114
Swiss-prot Accession numberQ6BEG6 (Sequence in FASTA format)
DescriptionAppetite-regulating hormone precursor (Growth hormone secretagogue)(Growth hormone-releasing peptide) (Motilin-related peptide)[Contains: Ghrelin; Obestatin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the motilin family.
Tissue SpecificityN/A
Post translational modification O-n-octanoylation is essential for ghrelin activity (By similarity). Amidation of Leu-98 is essential for obestatin activity (By similarity).
FunctionObestatin may be the ligand for GPR39. May have an appetite-reducing effect resulting in decreased food intake. May reduce gastric emptying activity and jejunal motility.
Protein Length117 Amino acids
Molecular weight12956
References1   Lin X., Miyazato M., Kaiya H., Ida T., Kangawa K.; "cDNA cloning of feline and caprine ghrelin."; Submitted (JUL-2002) to the EMBL/GenBank/DDBJ databases.
Domain NameMotilin_assoc  Motilin_ghrelin  
Hormone NameObestatin
Mature Hormone SequenceFNAPFDVGIKLSGAQYHQHGQAL
Position of mature hormone in Pre-Hormone protein23 Residues from position (76-98)
ReceptorN/A
Gene ID493844      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 3

HMRbase accession number10292
Swiss-prot Accession numberQ9MYK8 (Sequence in FASTA format)
DescriptionProrelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityExpressed by the placenta. Exclusively detected in cells located in the lamellar placental labyrinth and absent from other placental and nonplacental uterine parts
Post translational modificationN/A
FunctionRelaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals
Protein Length180 Amino acids
Molecular weight20360
References1  PubMed abstract 9915995
Domain NameInsulin  
Hormone NameRelaxin B chain
Mature Hormone SequenceQEEVLKACGREFVRLQIRICGSLSWG
Position of mature hormone in Pre-Hormone protein26 Residues from position (26-51)
ReceptorN/A
Gene ID493883      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 4

HMRbase accession number10293
Swiss-prot Accession numberQ9MYK8 (Sequence in FASTA format)
DescriptionProrelaxin precursor (RXN) [Contains: Relaxin B chain; Relaxin Achain].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted (By similarity)
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityExpressed by the placenta. Exclusively detected in cells located in the lamellar placental labyrinth and absent from other placental and nonplacental uterine parts
Post translational modificationN/A
FunctionRelaxin is an ovarian hormone that acts with estrogen to produce dilatation of the birth canal in many mammals
Protein Length180 Amino acids
Molecular weight20360
References1  PubMed abstract 9915995
Domain NameInsulin  
Hormone NameRelaxin A chain
Mature Hormone SequenceSDYIRYSDRCCNVGCTRKELADLC
Position of mature hormone in Pre-Hormone protein24 Residues from position (157-180)
ReceptorN/A
Gene ID493883      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 5

HMRbase accession number10325
Swiss-prot Accession numberQ52R90 (Sequence in FASTA format)
DescriptionThyrotropin subunit beta precursor (Thyroid-stimulating hormonesubunit beta) (TSH-beta) (TSH-B) (Thyrotropin beta chain).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionIndispensable for the control of thyroid structure and metabolism
Protein Length138 Amino acids
Molecular weight15483
References1  PubMed abstract 16122898
Domain NameCys_knot  
Hormone NameThyroid-stimulating hormone subunit beta (TSH-B) (Thyrotropin beta chain)
Mature Hormone SequenceFCFPTEYMMHVERKECAYCLTINTTICAGYCMTRDINGKLFLPKYALSQDVCTYRDFLYKTVEIPGCPHHVTPYFSYPVAVSCKCGKCNTDYSDCIHEAIKTNDCTKPQKSD
Position of mature hormone in Pre-Hormone protein112 Residues from position (21-132)
ReceptorQ9BGN4    Detail in HMRbase   
Gene ID554350      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 6

HMRbase accession number10415
Swiss-prot Accession numberP06884 (Sequence in FASTA format)
DescriptionPancreatic prohormone precursor (Pancreatic polypeptide) (PP)[Contains: Pancreatic hormone; Pancreatic icosapeptide] (Fragment).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the NPY family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPancreatic hormone is synthesized in pancreatic islets of Langerhans and acts as a regulator of pancreatic and gastrointestinal functions
Protein Length66 Amino acids
Molecular weight7483
References1  PubMed abstract 3827854
Domain NameHormone_3  
Hormone NamePancreatic hormone
Mature Hormone SequenceAPLEPVYPGDNATPEQMAQYAAELRRYINMLTRPRY
Position of mature hormone in Pre-Hormone protein36 Residues from position (1-36)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 7

HMRbase accession number10638
Swiss-prot Accession numberO77805 (Sequence in FASTA format)
DescriptionLutropin subunit beta precursor (Luteinizing hormone subunit beta)(LSH-beta) (LSH-B) (LH-B) (Lutropin beta chain).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit beta family.
Tissue SpecificityN/A
Post translational modification N/A
Function Promotes spermatogenesis and ovulation by stimulating the testes and ovaries to synthesize steroids
Protein Length143 Amino acids
Molecular weight15318
References1   Pukazhenthi B.S., Varma G.M., Brown J.L.; "Molecular cloning and sequence analysis of the cDNA for the felineluteinizing hormone beta subunit."; Submitted (SEP-1998) to the EMBL/GenBank/DDBJ databases.
Domain NameCys_knot  
Hormone NameLuteinizing hormone subunit beta (LSH-B) (LH-B)(Lutropin subunit beta)
Mature Hormone SequenceSREPLRPLCRPINATLAAENEACPVCVTFTTTICAGYCPSMMRVLPAALPPVPQPVCTYRELRFASVRLPGCPPGVDPVVSFPVALSCRCGPCRLSSSDCGGPRAQPLACDRPPLPGLLFL
Position of mature hormone in Pre-Hormone protein121 Residues from position (23-143)
ReceptorN/A
Gene ID493833      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 8

HMRbase accession number10680
Swiss-prot Accession numberP06884 (Sequence in FASTA format)
DescriptionPancreatic prohormone precursor (Pancreatic polypeptide) (PP)[Contains: Pancreatic hormone; Pancreatic icosapeptide] (Fragment).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the NPY family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionThe physiological role for the icosapeptide has not yet been elucidated
Protein Length66 Amino acids
Molecular weight7483
References1  PubMed abstract 3827854
Domain NameHormone_3  
Hormone NamePancreatic icosapeptide
Mature Hormone SequenceDRGETLDILEWGSPHAAAPR
Position of mature hormone in Pre-Hormone protein20 Residues from position (40-59)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 9

HMRbase accession number10705
Swiss-prot Accession numberQ9GL67 (Sequence in FASTA format)
DescriptionParathyroid hormone precursor (Parathyrin) (PTH).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein (By similarity)
Developmental StageN/A
Similarity Belongs to the parathyroid hormone family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion
Protein Length115 Amino acids
Molecular weight12921
References1   Toribio R.E., Kohn C.W., Leone G.W., Capen C.C., Rosol T.J.; "Molecular cloning of feline preproparathyroid hormone."; Submitted (OCT-2000) to the EMBL/GenBank/DDBJ databases.
Domain NameParathyroid  
Hormone NameParathyroid hormone (Parathyrin) (PTH)
Mature Hormone SequenceSVSEIQFMHNLGKHLSSVERVEWLRRKLQDVHNFVALGAPIAHRDGGSQRPRKKEDNVPAENHQKSLGEADKADVDVLIKAKSQ
Position of mature hormone in Pre-Hormone protein84 Residues from position (32-115)
ReceptorN/A
Gene ID493684      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 10

HMRbase accession number10737
Swiss-prot Accession numberP46404 (Sequence in FASTA format)
DescriptionSomatotropin precursor (Growth hormone).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted protein
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionPlays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues
Protein Length216 Amino acids
Molecular weight24454
References1  PubMed abstract 8654953
2  PubMed abstract 7642118
Domain NameHormone_1  
Hormone NameSomatotropin
Mature Hormone SequenceFPAMPLSSLFANAVLRAQHLHQLAADTYKEFERAYIPEGQRYSIQNAQAAFCFSETIPAPTGKDEAQQRSDVELLRFSLLLIQSWLGPVQFLSRVFTNSLVFGTSDRVYEKLKDLEEGIQALMRELEDGSPRGGQILKQTYDKFDTNLRSDDALLKNYGLLSCFKKDLHKAETYLRVMKCRRFVESSCAF
Position of mature hormone in Pre-Hormone protein190 Residues from position (27-216)
ReceptorN/A
Gene ID493931      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 11

HMRbase accession number10836
Swiss-prot Accession numberP06306 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12069
References1   Okamoto S., Morimatsu M.; "Cat insulin."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 3518635
Domain NameInsulin  
Hormone NameInsulin B chain
Mature Hormone SequenceFVNQHLCGSHLVEALYLVCGERGFFYTPKA
Position of mature hormone in Pre-Hormone protein30 Residues from position (25-54)
ReceptorN/A
Gene ID493804      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 12

HMRbase accession number10837
Swiss-prot Accession numberP06306 (Sequence in FASTA format)
DescriptionInsulin precursor [Contains: Insulin B chain; Insulin A chain].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the insulin family.
Tissue SpecificityN/A
Post translational modification N/A
Function Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver
Protein Length110 Amino acids
Molecular weight12069
References1   Okamoto S., Morimatsu M.; "Cat insulin."; Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
2  PubMed abstract 3518635
Domain NameInsulin  
Hormone NameInsulin A chain
Mature Hormone SequenceGIVEQCCASVCSLYQLEHYCN
Position of mature hormone in Pre-Hormone protein21 Residues from position (90-110)
ReceptorN/A
Gene ID493804      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 13

HMRbase accession number11013
Swiss-prot Accession numberP46403 (Sequence in FASTA format)
DescriptionProlactin precursor (PRL).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the somatotropin/prolactin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionProlactin acts primarily on the mammary gland by promoting lactation
Protein Length229 Amino acids
Molecular weight26282
References1  PubMed abstract 8654953
Domain NameHormone_1  
Hormone NameProlactin
Mature Hormone SequenceLPICPSGAVNCQVSLRDLFDRAVILSHYIHNLSSEMFNEFDKRYAQGRGFITKAINSCHTSSLPTPEDKEQAQQIHHEDLLNVILRVLRSWNDPLYHLVTEVRGLHEAPDAILSRAIEIEEQNRRLLEGMEKIVHQVHPGVRENEVYSVWSGLPSLQMADEDSRLFAFYNLLHCLRRDSHKIDSYLKLLKCRIVYDSNC
Position of mature hormone in Pre-Hormone protein199 Residues from position (31-229)
ReceptorN/A
Gene ID751517      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 14

HMRbase accession number11148
Swiss-prot Accession numberP01354 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11482
References1  PubMed abstract 1773057
2  PubMed abstract 5784957
Domain NameGastrin  
Hormone NameBig gastrin
Mature Hormone SequenceQLGLQGPPQQVADLSKKQGPWLEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein34 Residues from position (59-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 15

HMRbase accession number11149
Swiss-prot Accession numberP01354 (Sequence in FASTA format)
DescriptionGastrin precursor [Contains: Big gastrin (Gastrin 34) (G34); Gastrin].
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the gastrin/cholecystokinin family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionGastrin stimulates the stomach mucosa to produce and secrete hydrochloric acid and the pancreas to secrete its digestive enzymes. It also stimulates smooth muscle contraction and increases blood circulation and water secretion in the stomach and intestine
Protein Length104 Amino acids
Molecular weight11482
References1  PubMed abstract 1773057
2  PubMed abstract 5784957
Domain NameGastrin  
Hormone NameGastrin
Mature Hormone SequenceQGPWLEEEEAAYGWMDF
Position of mature hormone in Pre-Hormone protein17 Residues from position (76-92)
ReceptorN/A
Gene IDN/A
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated


Search Result - 16

HMRbase accession number11502
Swiss-prot Accession numberQ52R91 (Sequence in FASTA format)
DescriptionGlycoprotein hormones alpha chain precursor (Anterior pituitaryglycoprotein hormones common subunit alpha) (Follitropin alpha chain)(Follicle-stimulating hormone alpha chain) (FSH-alpha) (Lutropin alphachain) (Luteinizing hormone alpha chain) (LSH-alpha) (Thyrotropinalpha chain) (Thyroid-stimulating hormone alpha chain) (TSH-alpha).
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted
Developmental StageN/A
Similarity Belongs to the glycoprotein hormones subunit alpha family.
Tissue SpecificityN/A
Post translational modification N/A
FunctionN/A
Protein Length120 Amino acids
Molecular weight13513
References1  PubMed abstract 16122898
2  PubMed abstract 16122898
Domain NameHormone_6  
Hormone NameGlycoprotein hormones alpha chain
Mature Hormone SequenceFPDGEFTMQGCPECKLKENKYFSKLGAPIYQCMGCCFSRAYPTPARSKKTMLVPKNITSEATCCVAKAFTKATVMGNAKVENHTECHCSTCYHHKI
Position of mature hormone in Pre-Hormone protein96 Residues from position (25-120)
ReceptorQ5GJ04   Detail in HMRbase   
Q9BGN4    Detail in HMRbase   
Gene ID751819      
PDB IDN/A
Drugpediawiki
Comments


Search Result - 17

HMRbase accession number11527
Swiss-prot Accession numberQ9N2C1 (Sequence in FASTA format)
DescriptionLeptin;Alternative Name: Obesity factor; Precursor
Source organismFelis silvestris catus (Cat)
Taxonomical ClassificationEukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae;Felinae; Felis.
Subcellular locationSecreted (Probable)
Developmental StageN/A
Similarity Belongs to the leptin family.
Tissue SpecificityN/A
Post translational modification N/A
Function May function as part of a signaling pathway that acts to regulate the size of the body fat depot. An increase in the level of LEP may act directly or indirectly on the CNS to inhibit food intake and/or regulate energy expenditure as part of a homeostatic mechanism to maintain constancy of the adipose mass (By similarity).
Protein Length167 Amino acids
Molecular weight18584
References----
Domain NameLeptin  
Hormone NameLeptin
Mature Hormone Sequence
Position of mature hormone in Pre-Hormone protein
ReceptorN/A
Gene ID493838      
PDB IDN/A
Drugpediawiki
Comments!Receptor for this Hormone are either unknown or have not yet been curated